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Mukesh Patel School of Technology Management and Engineering
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Assistant Professor

Areas of specialization: Pharmacology, Neuropharmacology, Computer Aided Drug Design, Network Pharmacology, Mitochondrial Transplantation

Experience:

Academic Experience: 2.5 Years

Interest areas: Pharmacology, Neuropharmacology, Computer Aided Drug Design, Network Pharmacology, Mitochondrial Transplantation

Awards:

  1. Wiley Top cited Article 2022-2023 Smita Jain’s paper has been recognised as a top cited paper* in CELL BIOCHEMISTRY AND FUNCTION The role of fatty acid amide hydrolase enzyme inhibitors in Alzheimer’s disease
    1. *Among work published between 1 January 2022 – 31 December 2023.
  2. Young Research Award 2024, International Conference on “Explore cutting-edge Research & Innovation in Pharmaceutical, Life Sciences and Technology” on 16 March-(Saturday)-2024 organized by Department of Pharmacy, Career Point University, Kota, Rajasthan, India.
  3. Late Smt Khazani Devi Memorial Appreciation Award 2024” for presentation on ‘Discovery of Novel Fatty Acid Amide Hydrolase (FAAH) Inhibitors as Anti-Alzheimer’s Agents through Pharmacophore-Based Virtual Screening, Molecular Docking and Experimental Validation’ during Indo-Brazilian international symposium-2024 Organized by APP Madhya Pradesh state branch & APP Brazilian international branch At school of pharmacy, SAM global university, Bhopal, Madhya Pradesh, Indi In collaboration with app community & clinical pharmacy division.
  4. Young Women Researcher Award, “Women 2023 Excellence Awards”, Issued by Genesin of Educational Impressions, Dis. Haridwar, Uttarakhand, India.
  5. School Innovation Challenge Govt of Rajasthan (Aug 2022): Won 3rd prize, district level Tonk, OIC-STARTUPS, DOT and C, Govt of Rajasthan
  6. Received Gold Medal in Master’s in Pharmacy (Pharmacology) (Oct 2018): Banasthali Vidyapith, Banasthali, Rajasthan.

Patents:

  1. A Novel Therapeutic Formulation of Exogenous Mitochondria Loaded with Nanocarrier and Method Thereof for Use in Mitochondrial Dysfunction Disorders
    Indian Patent Application No. 202511004283 A, Published, 31 January 2025.
  2. Novel Tetrazole Annulated Benzopyridodiazepinones
    Indian Patent Application No. 202411092416, Filed, December 2024.
  3. Smart Insulin Dispensing Device
    Indian Patent Application No. 417684-001, Published, July 2024.
  4. A Herbal Nanoemulsion
    Indian Patent Application No. 202311013825, Filed, 2023.
  5. A Polyherbal Nanosuspension
    Indian Patent Application No. 202211074013, Filed, 2023.
  6. Novel 3,5-Dimethyl Pyrazole Compounds, Method of Preparation and Pharmaceutical Compositions Thereof
    Indian Patent Application No. 202211008306, Filed, 2022.

Books/Book chapters published:

  1. Ashwini Kumar Mishra, Divya Sharma, Rahul Maurya, Smita Jain, Chandrashekhar Y. Jagtap (2025), “Medicinal Plants and Sustainable Human Health”, Innovations in Ayurvedic Nutrition, Springer Nature, 2025, 263–304.
  2. Devesh Kapoor, Smita Jain, Seema Patil, Shivangi Jaiswal, Jaya Dwivedi, Swapnil Sharma (2024), “Functionalized Magnetic Nanoparticles for Photothermal and Photodynamic Therapy”, Functionalized Magnetic Nanoparticles for Theranostic Applications, Wiley, 2024, 251-282.
  3. Payal Kesharwani, Smita Jain, Kanika Verma, Jaya Dwivedi, Swapnil Sharma (2024), “Functionalized Magnetic Nanoparticles for Chemotherapy Applications”, Functionalized Magnetic Nanoparticles for Theranostic Applications, Wiley, 2024, 377-416.
  4. Smita Jain, Ajita Paliwal, Arnav Walia (2024), “Role of Electroanatomic mapping in cardiovascular disease”, The Pulse of Cardiology, Nova Science Publishers, 2024, 297-322.
  5. Akansha Bisht, Smita Jain, Jaya Dwivedi, Swapnil Sharma (2024). “Emerging therapeutic role of cannabis in neurological disorders”. Cannabis and its Derivatives. Elsevier, May 2024, 165-204.
  6. Devesh Kapoor, Kanika Verma, Smita Jain, Swapnil Sharma (2024), “Gelatin-based Hydrogels for Drug Delivery: A Recent Update”. Biomaterial-based hydrogels, Springer, April 2024, 67-87.
  7. Payl Kesharwani, Kajal Kumari, Smita Jain, Swapnil Sharma (2023), “Barriers to targeted drug delivery strategies in the brain”. Brain Tumor Targeting Drug Delivery System, Bentham Science Publisher. Sept 2023, 34-59.
  8. Swati Paliwal, Ashish Sharma, Smita Jain, Swapnil Sharma (2023), “Machine learning and deep learning in bioinformatics”. Bioinformatics and Computational Biology. Taylor and Francis Group, November 2023, 1-12w.
  9. Payal Kesharwani, Ankit Jain, Smita Jain, Vivek Dave, Swapnil Sharma (2022), “Colloidosome as an efficient novel drug delivery system: An update”. Advanced Pharmaceutical and Herbal Nanoscience for Targeted Drug Delivery System Part II, Bentham Science, Page no 141-165.
  10. Neha Chauhan, Smita Jain, Kanika Verma, Swapnil Sharma, Raghuraj Chouhan, Veera Sadhu (2022), “Impact of calcium ions (Ca2+) and their signalling in Alzheimer’s and other neurological-related disorders”. Smart Nanodevices for Point-of-Care Applications, Taylor and Francis Group, Page no 323-328.
  11. Smita Jain, Neha Chauhan, Swapnil Sharma, Raghava Reddy Kakarla, Veera Sadhu, Raghavendra V. Kulkarni (2020), “The link between anxiety and Alzheimer’s disease: critical facts”. Nanomaterials in Diagnostic Tools and Devices, Elsevier, Edition 1st, Page no 331-350.

Number of Publications: 50

Recent Publications: (Last three years)

  1. Ashwini Kumar Mishra, Smita Jain* (2025). Integrative Multiomics Insights into the Genetic and Epigenetic Architecture of Alzheimer’s Disease. ACS Chemical Neuroscience. If-4.2 https://doi.org/10.1021/acschemneuro.5c00750
  2. Praisthy L.J. Ravi, Kushwaha. Sachin Dubey. Vipin Kumar, Smita Jain (2025). Pharmacotherapeutic potential of daidzein : insights into mechanisms and clinical relevance, Inflammopharmacology. IF-5.3 https://doi.org/10.1007/s10787-025-01891-y.
  3. Smita Jain*, Reetuparna Acharya, Lavkush Verma, Aparna Chauhan (2025). Harnessing Metabolism to Combat Neurodegeneration: Strategies for Reversing Age-Related Cognitive Decline, ACS Pharmacology and Translational Science, 8(9), 2868-2886. IF- 4.3 https://doi.org/10.1021/acsptsci.5c00077.
  4. Ravi Kushwah, Smita Jain*, Meenal Sahu, Chinchu Praisthy LJ, Siddharth Maurya, Taufik Ansari, Mansi, Ashwini Kumar Mishra, Aleksey Kuznetsov (2025). Mechanistic insights into the antidiarrheal action of phlorizin: modulation of TLR4/NF-κB, PI3K/AKT, and HIF-1 signalling with antispasmodic and antimicrobial effects. Naunyn-Schmiedeberg’s Archives of Pharmacology. 1-17. IF-3.1
  5. Chandola Preeti, Smita Jain*, Singh Ritu, Jamali Mohammad Chand, Dwivedi Jaya, Sharma Swapnil, Keli Kelvin M, Kuznetsov, Aleksey E (2025). Receptor-based pharmacophore modelling for the discovery of Sirtuin 1 modulators in Alzheimer’s disease. Analytical Chemistry Letters, 15(4), 637–652. IF-1.6. https://doi.org/10.1080/22297928.2025.2514856
  6. Smita Jain*, Ritesh Bhole, Sonali Labhade (2025). Unveiling the anti-Alzheimer potential of flavonoids: A comprehensive in-silico study, Vietnam Journal of Chemistry. 1–14. https://doi.org/10.1002/vjch.70051.
  7. Chinchu Praisthy L J, Ravi Kushwah, Sachin Dubey, Sonali Labhade, Pawan Karwa, Smita Jain*, (2025). Daidzein targets PI3K-Akt signalling and oxidative stress in glioblastoma: An Integrated pharmacological and in vitro study, Brain Research, 1863, 149840. IF – 2.5. https://doi.org/10.1016/j.brainres.2025.149840.
  8. Ashwini Kumar Mishra, Pravat Kumar Sahoo, Rajesh Singh, Smita Jain* (2025), “Tectoridin modulates intertwined molecular pathways in metabolic syndrome: insights from network pharmacology, molecular docking, and in vivo studies”, Inflammopharmacology. IF-5.3 https://doi.org/10.1007/s10787-025-01815-w
  9. Surendra Kumar Gautam, Rakesh Kumar Paul, Smita Jain*, Vipin Kumar, Kaisar Raza** (2025), “GC–GC-MS Profiling and Computational Analysis of Balanites aegyptiaca phytoconstituents for antidiabetic activity: insights from network pharmacology and molecular docking”, Naunyn-Schmiedeberg’s Archives of Pharmacology. IF- 3.1, https://doi.org/10.1007/s00210-025-04187-8
  10. Smita Jain, Kaisar Raza (2025), “Brain Targeting Using Nanocolloids for the Management of Multiple Sclerosis”, Current Drug Delivery. IF-3 2174/0115672018330624241125060045
  11. Smita Jain, Ritu Singh, Tripti Paliwal, Kanika Verma, Jaya Dwivedi, Sarvesh Paliwal, Swapnil Sharma (2024) “Discovery of novel fatty acid amide hydrolase (FAAH) inhibitors as anti-Alzheimer agents via in-silico-based drug design, virtual screening, molecular docking, molecular dynamics simulation, DFT, and non-clinical studies”, Pharmacology, Biochemistry and Behavior, 247, 173943. IF – 3.3, https://doi.org/10.1016/j.pbb.2024.173943
  12. Smita Jain*, Ankita Murmu, Saraswati Patel (2024), “Elucidating the therapeutic mechanism of betanin in Alzheimer’s Disease treatment through network pharmacology and bioinformatics analysis”, Metabolic Brain Disease, 39, 1175-1187. IF- 3.2, https://doi.org/10.1007/s11011-024-01385-w
  13. Smita Jain*, Sonali Labhade, Ritesh Bhole (2024), “CyPD inhibition for Alzheimer’s: In silico screening of phytochemicals from Asian medicinal plants”, Indian Journal of Chemistry, 63, 473-484. IF- 0.8, https://doi.org/10.56042/ijc.v63i5.8969
  14. Khushboo Bhardwaj, Shivangi Jaiswal, Annu Bhardwaj, Deepika Arora, Smita Jain, Gulshan Kumar, Jaya Dwivedi, Swapnil Sharma (2025), “Unveiling novel thiadiazolo-annulated azepine hybrids as peptide deformylase inhibitor: DFT, molecular docking and ADMET studies”, Journal of Molecular Structure, 1336, 142105. IF – 4.0, https://doi.org/10.1016/j.molstruc.2025.142105
  15. Akanksha Chaturvedi, Kanika Verma, Smita Jain, Pragya Sharma, Vartika Paliwal, Sarvesh Paliwal, Swapnil Sharma (2024), “Nyctanthes arbor-tristis improves blood pressure via endothelial pathway: in silico, ex vivo, and in vivo evidence”, Cell Biochemistry and Biophysics, 83(2):1861-1877.   IF-1.8, 1007/s12013-024-01594-1
  16. Pooja Chak, Akansha Bisht, Deepti Choudhary, Smita Jain, Priyanka Joshi, Sonika Jain, Pankaj Jain, Jaya Dwivedi, Swapnil Sharma (2024), “In vitro cox inhibitory activity, LC-MS analysis and molecular docking study of Silene vulgaris and Stellaria media”, Cell Biochemistry and Biophysics, 83(1):1009-1020. IF – 1.8, 1007/s12013-024-01533-0
  17. Smita Jain, Swapnil Sharma, Ajita Paliwal, Jaya Dwivedi, Shailendra Paliwal, Vartika Paliwal, Sarvesh Paliwal, Jaiprakash Sharma (2023), “Discovery of novel fatty acid amide hydrolase (FAAH) inhibitors as anti-Alzheimer’s agents through pharmacophore-based virtual screening, molecular docking and experimental validation”. Medicinal Chemistry Research, 33, 136-150. IF – 2.6, https://doi.org/10.1007/s00044-023-03170-3
  18. Shivangi Jaiswal, Dharma Kishore, Annu Bhardwaj, Khushboo Bhardwaj, Shruti Richa, Smita Jain, Jaya Dwivedi, Swapnil Sharma (2024), “Water-assisted cascade synthesis of trifluoromethylated dipyridodiazepinone analogues: in vitro and in silico antibacterial studies”, Organic and Biomolecular Chemistry, 22, 6520-6531. IF – 2.9, https://doi.org/10.1039/D4OB00828F
  19. Sonali Labhade, Smita Jain, Sohan Chitlange, Sarvesh Paliwal, Swapnil Sharma (2023), “Decalepis hamiltonii root fraction alleviates CCl4 hepatotoxicity in a rat model”. Journal of Ayurveda and Integrative Medicine, 14(6), 100818. IF – 2.6, https://doi.org/10.1016/j.jaim.2023.100818
  20. Swati Paliwal, Smita Jain, Pallavi Mudgal, Kanika Verma, Sarvesh Paliwal, Swapnil Sharma (2023), “Mitochondrial transfer restores impaired liver functions by AMPK/mTOR/PI3K-AKT pathways in metabolic syndrome”. Life Sciences, 332, 122116. IF – 5.2, 1016/j.lfs.2023.122116
  21. Jigar Panchal, Shivangi Jaiswal, Sonika Jain, Jyoti Kumawat, Ashima Sharma, Pankaj Jain, Smita Jain, Kanika Verma, Jaya Dwivedi, Swapnil Sharma (2023), “Development of novel bosentan analogues as endothelin receptor antagonists for pulmonary arterial hypertension”. European Journal of Medicinal Chemistry, 259, 115681. IF – 6.0, https://doi.org/10.1016/j.ejmech.2023.115681
  22. Ritika Gururani, Saraswati Patel, Akansha Bisht, Smita Jain, Sarvesh Paliwal, Jaya Dwivedi, Swapnil Sharma (2023), “Tylophora indica (Burm. f.) Merr alleviates tracheal smooth muscle hyperresponsiveness in ovalbumin-induced allergic-asthma model in guinea-pigs: Evidence from ex vivo, in silico and in vivo studies”. Fundamental and Clinical Pharmacology, 37(6):1153-1169. IF – 2.1, 1111/fcp.12927
  23. Ajita Paliwal, Smita Jain, Sarvesh Paliwal (2023), “Molecular modelling, docking, and QSAR studies on a series of n-arylsulfonyl-n-2-pyridinyl-piperazines analogs acting as anti-diabetic agents”. Trends in Sciences, 20(7), 5472-5472. IF – 0.8, https://doi.org/10.48048/tis.2023.5472
  24. Sonali Labhade, Smita Jain, Sohan Chitlange, Swapnil Sharma (2023), “LC/MS characterization of secondary metabolites of Sphagneticola trilobata F Pruski Leaves”. Journal of Pharmaceutical Negative Results, 1278-1283.
  25. Meenu Devi, Shivangi Jaiswal, Neetu Yaduvanshi, Sonika Jain, Smita Jain, Kanika Verma, Rahul Verma, Dharma Kishore, Jaya Dwivedi, Swapnil Sharma (2023), “Design, synthesis, molecular docking, and antibacterial study of aminomethyl triazolo substituted analogues of benzimidazolo [1, 4]-benzodiazepine”. Journal of Molecular Structure, 1286, 135571. IF – 4.0, https://doi.org/10.1016/j.molstruc.2023.135571
  26. Akansha Bisht, Ritika Gururani, Smita Jain, Rahul Shukla, Jaya Dwivedi, Swapnil Sharma (2023), “Cedrus deodara (Roxb. ex D. Don) G. Don bark fraction ameliorates metabolic, endocrine and ovarian dynamics in rats experiencing polycystic ovarian syndrome”. Journal of Ethnopharmacology, 306(6), 116206. IF – 4.8, https://doi.org/10.1016/j.jep.2023.116206

 

Dissertations/Projects Guided: 8 (PI – 3, Co-PI – 5)

Professional memberships:

  1. Indian Association of Neuroscience (Member ID: LJ-61)
  2. Association of Pharmacy Professionals (Member ID: APP/RJ/L<-224/24]
  3. Association of Pharmaceutical Teachers of India (Member ID: RA/LM-670, dated – 14/Aug/2023)
  4. Society of Pharmaceutical Education & Research (SPER) (Membership ID: SPER/LM/RJ/184)